Microscopic methods are generally used to characterize biological cell and tissue samples. However, the process of obtaining microscopic images for use in examining large-scale compounds is extremely time-consuming. The Fraunhofer IPT has developed a high-throughput method of fluorescence microscopy which enables entire, extensive areas of a sample, such as adherent cells in microtiter plates, to be examined rapidly. On this basis, we are currently developing multi-modal imaging, which combines light sheet and full field optical coherence microscopy for 3D cell cultures and organoids. This also permits pathological compounds to be digitalized rapidly in high resolution. Instead of procuring new and expensive slide scanners, existing microscopes can be upgraded cost-efficiently and users benefit from the availability of a high through-put slide scanner with the full flexibility of the microscope.